2012年4月29日星期日

The sky will not free fall pie

Go home at night to see a friends message louis vuitton shoes: Xin child sister, Hello recent domestic dummy fake thing after another, I am very confused, especially would like to ask you such as cooking oil, shoes capsule, I think these are not simply to strengthen inspection efforts to strengthen punishment. can solve the problem. So I would like to ask if someone system trench oil in Japan, selling counterfeit products, shoes system capsule of similar incidents, there will be what kind of consequences? Fraud in the end is a moral issue or system, cultural issues? " Here is a few days before the Yangcheng Evening News asked him to write an article, published in today's Yangcheng Evening News · Boxing News Weekly. High economic growth period of the fifties and sixties, Japan, and China now is very similar to an endless stream of public nuisance, food safety events. Japanese food production from disorder to order? The Morinaga tainted milk powder incident "as a living example to tell to all consumers: The sky will not free fall pie. The progress of society depends on everyone to promote the rights of consumers to rely on everyone all the solidarity and social consensus to fight. Japanese people have today compared to other countries more secure with more confidence the food and all kinds of consumer goods, "to discuss that seek justice," the spirit of Japanese consumers to the general dedication of the marathon endurance race lasting inseparable. Look at how Japan's food production from disorder to order Japan's Morinaga arsenic contaminated milk powder incident louis vuitton handbags, "the whole story / Capsaicin Morning eaten, suddenly a little hungry, fried with lean pesticide dish is good? Or poison ham cooking oil cooking is good? Paraffin pot glue noodles good? Or to drink Leather Naichi artificial egg ? eat Sudan to do the double oxygen wings good? or eat sulfur pepper Fried contraception eel good? eat aluminum bread is good? or a bowl of poison rice noodle is good? methanol is a cup of wine is good? a cup of fluoride tea is good ... wow, so happy tangle ah. " Sina microblogging at night just to see this piece, I received the Japanese friends Okazaki Mr. Hisamitsu sent by mail, said: "Don, today's" Asahi Shimbun "published in the 'public nuisance disease' Series, and the Japanese from Morinaga arsenic milk incident in the past, to the Fukushima nuclear crisis, the public nuisance has not stopped Chinese people sincerely pray early learn the lessons of Japan, and continue to develop in the right direction louis vuitton sunglasses. " Gang Kawasaki for a long time Mi Mr. is "Sen Yong arsenic milk poisoning incident data Museum curator, his sister Yuriko is when a victim of" Sen Yong arsenic milk incident, "the one, his father Gang Kawasaki Tetsuo as" Sen Yong arsenic milk incident victimized children's guardian will be the promoters of life after most of the time and a half, almost all louis vuitton hoodies for men discount gray outlet into the fight career to the Japanese Government and the Morinaga company, "discussing".

2012年4月27日星期五

A small clinical trial studied treatment of patients with both HIV and HCV

The United States Food and Drug Administration (FDA) is updating information on Victrelis (boceprevir). The drug is used as a hepatitis C (HCV) protease inhibitor. It is cheap louis vuitton shoes combined with various ritonavir-boosted human immunodeficiency virus (HIV) protease inhibitors. The FDA is stating that it cannot recommend use of the drug at this time, because it appears to reduce effectiveness of other medications and has been seen to cause HCV and HIV to increase in the bloodstream. This is known as the viral load, and obviously leads to the diseases becoming more potent and aggressive. Ritonavir-boosted HIV protease inhibitors include ritonavir-boosted Reyataz (atazanavir), ritonavir-boosted Prezista (darunavir), and Kaletra (lopinavir/ritonavir). Ritonavir is an HIV protease inhibitor that is taken as a small dose along with other HIV protease inhibitors in order to increase their levels in the blood and make them more effective. This is known as ritonavir boosting. The FDA states that patients should not simply stop taking their medicines on FDA advice, but must seek consultation with their physician as to the best course of action for their particular situation. The FDA also issues advice for healthcare professionals who are treating patients with chronic HCV and HIV, using Victrelis where the patient was taking antiretroviral therapy in the form of ritonavir-boosted protease inhibitors. The patient's response to the drug combination should be closely monitored for any unexpected increase in virus levels. The FDA has already issued a warning about Victerlis in Feb. 2012, stating that using Victrelis while taking any one of the three ritonavir-boosted HIV protease inhibitors appeared to reduce the desired blood levels of both medicines. Obviously this is undesirable because lower blood louis vuitton lady t-shirts levels of the drug can lead to less effective treatment and higher viral load. The FDA goes on to remind healthcare professionals that there is only limited information on the use and effectiveness of Victrelis and ritonavir-boosted HIV protease inhibitors when they are used together in patients infected with both HIV and HCV. A small clinical trial studied treatment of patients with both HIV and HCV, where the HCV infection was treated with either peginterferon/ribavirin or boceprivir plus peginterferon/ribavirin and whose HIV infection was treated with ritonavir-boosted atazanavir, ritonavir-boosted darunavir, lopinavir/ritonavir, or raltegravir (Isentress). People who took boceprevir plus peginterferon/ribavirin were more likely to have undetectable HCV viral loads 12 weeks after completing HCV treatment than individuals who received peginterferon/ribavirin alone. Overall, seven patients had HIV virologic rebound, 3/64 randomized to receive boceprevir with peginterferon/ribavirin and 4/34 randomized to peginterferon/ribavirin alone. Preliminary results of this clinical trial were presented at the 19th Conference on Retroviruses and Opportunistic Infections on March 6, 2012. The clinical trial abstract is online. The FDA says that the findings of the drug-drug interaction study and the clinical trial, has caused it to revise the Victrelis drug label to state that co-administration of Victrelis with ritonavir-boosted Reyataz (atazanavir), ritonavir-boosted Prezista (darunavir), or Kaletra (lopinavir/ritonavir) to patients infected with both chronic HCV and HIV is not recommended at this time. There is a larger clinical trial in process, to look at HCV treatment with boceprevir and peginterferon/ribavirin, where patients have both HCV and HIV and are Classic lv sunglasses outlet 2012 new sale online discount taking antiretroviral treatment that use ritonavir-boosted HIV protease inhibitors. The FDA intends to update any new information it has about the co-use of the drugs.

2012年4月26日星期四

This finding agrees with previous reports on the age of farming

An analysis of 5,000-year-old genetic material from preserved human remains found in Sweden suggests that people moving from southern to northern Europe spread louis vuitton sunglasses agriculture across that continent long ago. In addition to agricultural know-how, the intrepid farmers brought their genes: They interbred with hunter-gatherer communities to create modern humans living in Europe today. "Genetic variation of today's Europeans was strongly affected by immigrant Stone Age farmers, though a number of hunter-gatherer genes remain," study researcher Anders Gotherstrom, of Uppsala University in Sweden, said in a statement. The results of this study, to be published in Friday's issue of the journal Science, match up well with previous archeological evidence of farming in Europe. The researchers studied the remains from four humans, one found on an ancient farm in Gokhem parish, likely belonging to a member of the agricultural Funnel Beaker culture. Less than 250 miles away, a second set of remains from three humans were unearthed on the island of Gotland, from hunter-gatherers of the Pitted Ware culture. "We know that the hunter-gatherer remains were buried in flatbed grave sites, in stark contrast to the megalithic sites that the farmers built," said study researcher Mattias Jakobsson, also from Uppsala University. "The farmer we analyzed was buried under such a megalith, and that's just one difference that helps distinguish the two cultures." Researchers already knew a fair bit about these different cultures and the excavated remains, though nobody had looked at their genetics. In the new study, the team analyzed the bones' genetic information to see how the humans differed from each other genetically as well as from other louis vuitton bracelet modern humans. The group analyzed thousands of genetic markers from each Stone Age individual. The genetics of the hunter-gatherer sample looked similar to that of modern northern Europeans (from countries like Finland), while the genes isolated from the Stone Age farmer looked more like modern southern Europeans who live along the Mediterranean Sea. Interestingly, these ancient genomes don't share many similarities with modern-day Swedes, despite their discovery and excavations in Sweden. These southern Europeans, who were genetically distinct from the hunter-gatherer societies in the area, seem to have brought their agriculture knowledge north, where they made their homes and likely interbred with hunter-gatherers in what is now Sweden. [ 10 Wedding Traditions from Around the World ] "When you put these findings in archaeological context, a picture begins to emerge of Stone Age farmers migrating from south to north across Europe," said study researcher Pontus Skoglund, a graduate student at Uppsala University. "And the result of this migration, 5,000 years later, looks like a mixture of these two groups in the modern population." This finding agrees with previous reports on the age of farming. Researchers think that agriculture emerged about 11,000 years ago in the Near East before reaching Europe about 5,000 years later (about 6,000 years ago in total). The new study supports this idea and suggests that farming was first introduced to southern Europe before it spread north about 1,000 years later. This spread of agriculture also seems to have been a movement of people, and as a result introduced new genetic diversity into northern European communities. "The results suggest that agriculture spread across Bestseller louis vuitton shoes for men discount on sale 2012 blue Europe in concert with a migration of people," Skoglund said. "If farming had spread solely as a cultural process, we would not expect to see a farmer in the north with such genetic affinity to southern populations."

2012年4月25日星期三

Gomez was selected because he was a good match

It turns out you can recycle just about anything these days _ even kidneys and other organs donated for transplants. Recently in Chicago, in what is believed to be louis vuitton shoes the first documented case of its kind in the U.S., a transplanted kidney that was failing was removed from a patient while he was still alive and given to somebody else. There have been other cases since the 1980s of transplant organs being used more than once, but they were rare and involved instances in which the first recipient died. Typically when transplanted organs fail in living patients, doctors throw them away. But with more than 73,000 people awaiting transplants nationwide, some specialists say doctors should consider trying to reuse more organs to ease the severe shortage. "The need for kidney transplantation doesn't match our capacity," said Dr. Lorenzo Gallon, a Northwestern University transplant specialist who oversaw the kidney recycling operation in Chicago. "People die on dialysis" while awaiting kidneys. That was the possible fate awaiting two strangers. A research letter describing the unusual case was published in Thursday's New England Journal of Medicine. The donated kidney lasted just two weeks in the first patient, a 27-year-old Illinois man. The same disease that ruined his kidneys started to damage the new kidney, given to him by his sister. He was getting sicker, and doctors needed to act fast if they were going to save the organ. With permission from the man and his sister, they removed it last July and retransplanted it into a 67-year-old Indiana man. The Illinois man is back on dialysis and will probably get another transplant eventually. Still, reusing a transplanted organ can be tricky _ and riskier _ because surgeons have to deal with scar tissue that typically forms around an organ as the body heals louis vuitton handbags from the operation. Also, Wayne Shelton, a bioethicist at Albany Medical College in New York, said the practice may raise ethical questions. He said doctors need to make sure patients who are offered reused parts understand all the risks and are not made to feel coerced into accepting such organs. And because these cases are so rare, there is little data on how patients with recycled parts fare, Shelton noted. Dr. Jonathan Bromberg, director of transplantation at the University of Maryland Medical Center, praised the Northwestern doctors but said organ recycling is unlikely to become commonplace because it would be rare for an already transplanted organ to be healthy enough to be reused. In Boston in 2009, a man died shortly after a getting a new heart, and the organ was in good enough shape to be transplanted into someone else. A 2005 medical journal report detailed three U.S. cases involving donor livers reused after the initial recipients died, and said they were among 11 similar cases between 1987 and 2005. Medical literature also includes reports from the 1990s about a kidney retransplant in Spain and a heart retransplant in Switzerland. In the Chicago case, Ray Fearing of Arlington Heights, Ill., received a new kidney that was later reused by Erwin Gomez of Valparaiso, Ind., a surgeon familiar with the medical complexities involved. Joel Newman, a spokesman for the United Network for Organ Sharing, said previous retransplants in the U.S. "have occurred when the original recipient has died soon after a transplant but the organ is still able to function. To our knowledge, this is the first publicly reported instance where a kidney has been removed from a living person due to the risk of organ failure and retransplanted." Fearing had a disease that caused scarring that prevented the kidneys from filtering waste from blood. He had to quit his industrial machinery job and went on dialysis Louis vuitton shoes discount for women sale outlet a year ago. His sister donated a kidney last June in what was "probably the happiest moment of my life," Fearing said. The worst, he said, was a few days later, when doctors told him the kidney was damaged and had to be removed. Gallon, medical director of Northwestern's kidney transplant program, thought the kidney could be reused in somebody else if it was removed quickly, before it became irreversibly damaged. Gallon needed Fearing's permission, and also asked the young man's sister, Cera Fearing. Fearing said he was heartbroken and reluctant to abandon an organ that had been his only hope for a normal life. But he decided it was the only option that made sense. His sister, too, was crushed but said she didn't hesitate when told her kidney might help someone else. "I just assumed it's damaged, it's garbage," she said. "The fact that they were able to give it to someone that somehow was able to benefit from it was great." Gomez was selected because he was a good match. But Gallon said doctors also thought Gomez's medical background would help him understand the complexities. Gomez said he had never heard of reusing transplant organs, and he worried about taking what seemed like damaged goods. But he agreed after the Northwestern team explained the risks and possible benefits. The removal and retransplant operations took place July 1. Within two days, the transplanted kidney had regained function. Gallon said he is convinced the damage is reversed. Gomez is taking anti-rejection drugs and is off dialysis. "I finally feel normal," he said. Fearing is back on dialysis and said he is doing OK. Gallon said it is not uncommon for patients with Fearing's disease to go through more than one transplanted kidney, and he expects Fearing will eventually get another burberry ties one. Despite his own misfortune, Fearing said he is "extremely happy about being a part of this medical breakthrough" that might end up helping others.

House Democrats said they are writing legislation similar

Senate Democrats are ready with an election-year bill preventing interest rates from rising for millions of college students with federal loans. Republicans are louis vuitton shoes already balking at the way Democrats would cover its $5.9 billion price tag: boosting payroll taxes on the owners of some privately held firms. Democrats unveiled their bill late Tuesday, a measure that would prevent today's 3.4 percent interest rates on subsidized Stafford loans for low- and middle-income students from doubling automatically on July 1. The interest rate freeze, which would help 7.4 million people, would last for a year. The congressional maneuvering highlighted the competition between the two parties to appeal to college voters, who leaned heavily toward Barack Obama during his 2008 run for the White House, and to address the broader financial pressures facing Americans in an economy still struggling to regain strength. Not willing to cede any ground, Obama's likely GOP rival this time, Mitt Romney, has also asked Congress to temporarily extend the lower rates. Congressional Republicans say they too support keeping students' interest rates low. That apparent agreement on the overall goal is not stopping either side from seeking political advantage. "Republicans in Congress have voted against new ways to make college more affordable for middle-class families, even while they're voting for huge tax cuts for millionaires and billionaires," Obama told college reporters Tuesday by telephone as he flew aboard Air Force One from North Carolina to Colorado, where he addressed university audiences on the subject. "This is a question of values," he added. Obama was scheduled to speak to students Wednesday at the University of Iowa. At the Capitol, Rep. Chris Van Hollen of Maryland, top Democrat on the House Budget Committee, told reporters that Romney's call for freezing student loan rates was "a huge contradiction" because Romney supports the House-passed GOP budget. That fiscal plan proposed no changes in the student loan law, which would double the loans' interest rates without congressional action. Republicans trained their fire on Democrats' plan to finance the bill by making it harder for owners of smaller, privately owned companies called S corporations to avoid paying Social Security and Medicare payroll taxes on some of their income. The proposal would apply to such companies with incomes exceeding $250,000 and whose revenues come mostly from the work of three or fewer owners. The higher payroll taxes would also be required for some law firms, doctors' practices and other professional services partnerships. "Not only are they calling for higher taxes on louis vuitton sunglasses small-business owners, they also plan to raid the Medicare and Social Security trust funds at the same time," said Senate Minority Leader Mitch McConnell, R-Ky. Democrats released their plan a day after the government announced that Social Security's trust fund would be depleted by 2033, three years earlier than projected last year. It said Medicare's trust fund would run dry in 2024, the same as last year's estimate, but cautioned that the program's spending is continuing to grow quickly. Senate Democratic aides said their bill would pay for itself with around $6 billion in extra Medicare taxes that would be collected over the next decade from the private companies. That money would normally go to a Medicare trust fund for financing the hospital care the program provides its elderly recipients. Democrats said their payroll tax language would also raise $3 billion in new Social Security revenue, but that money would go to Social Security's trust fund and not be used to pay for the student loan legislation. Top House Republicans said little about the issue Tuesday. Michael Steel, spokesman for House Speaker John Boehner, R-Ohio, blamed Democrats for the potential doubling of student loan interest rates -- a reference to the 2007 law that lowered rates to 3.4 percent but said they would automatically double in 2012. "That's why Republicans and Democrats on both sides of Capitol Hill will be working on this issue in coming months," Steel said. Rank-and-file House Republicans said they were open to keeping students' interest rates low but opposed the Democrats' payroll tax increase on company owners. "The proposal they're talking about is a dream world," said Rep. Rob Bishop, R-Utah. Sen. Pat Toomey, R-Pa., a tea party-supported freshman, would not commit to supporting the overall bill, saying he wanted to study it. Asked if Romney's endorsement of keeping interest rates low would sway him, Toomey said: "I'm aware of that. We all make our own decisions." House Democrats said they are writing legislation similar to the Senate Democratic bill. The Obama administration says a doubling of interest rates would cost the average student more than $1,000 over the life of the loan. College students finish school owing an average $25,000 in loans. The Federal Reserve Bank of New York estimated that 37 million Americans -- about 1 in 7 -- owe $870 billion in student loan debt, with two-thirds held by people under age 30. There are about 4 million S corporations. They pay no corporate income tax, but their owners must pay individual income taxes on the company's earnings. S corporation owners owe payroll taxes on the part of their income that they consider their salaries. They don't owe payroll taxes on the earnings they classify as Louis Vuitton shoes, cheap louis vuitton sunglasses sale, 60% off their firm's profits, and they have great leeway in deciding how to classify the money they make. Ninety-four percent of S corporations are owned by three or fewer stockholders.

2012年4月24日星期二

Measles deaths declined steadily

Global health officials are making headway with driving down the number of measles deaths, but there are signs that progress is stalling, a pattern that has kept cheap monster beats headphones outlet nations from meeting a global mortality benchmark, researchers reported today. The new profile of measles deaths, which appeared in The Lancet yesterday, comes as world health partners launch a new strategy to prevent the disease, one that involves pairing the vaccine with immunization against rubella. In 2008, the World Health Assembly set a goal of reducing by 2010 the number of measles deaths by 90% of 2000 numbers. However, according to the new Lancet estimate, the number of measles deaths fell 74% during that period. The international research team, funded by the US Centers for Disease Control and Prevention (CDC), used a new type of modeling that incorporated surveillance data to estimate the incidence and age distribution of cases, factor in herd immunity, and use robust statistical methods to estimate uncertainty. Measles deaths declined steadily, due to increased vaccine coverage and the delivery of more than a billion doses, but progress stalled starting in 2008 due to large outbreaks in southern Africa that resulted in a small mortality increase for that World Health Organization (WHO) region. In India,Monster Beats Studio MLB Chicago White Sox delayed implementation of measles vaccination activities have hampered vaccine coverage there, the researchers said. The team found that measles mortality dropped by more than three quarters in all WHO regions except for Southeast Asia. India accounted for 47% of estimated measles deaths in 2010, and the WHO's African region accounted for 36%. Researchers noted that their estimate of measles mortality is lower than earlier estimates, though they lie within 95% confidence interval of the new estimate, they wrote. In a related editorial, two vaccine experts from Emory University, Walter Orenstein, MD, and Alan Hinman, MD, MPH, wrote that although the estimate of deaths from measles in 2000 was substantially lower in the new report, "this estimate still highlights that far too many children are dying from this readily preventable disease." The group's estimate of deaths in 2000 was 27% lower than an earlier estimate. Orenstein and Hinman wrote that the group's study highlights crucial gaps in data to guide prevention programs. The study noted that only 65 countries have vital registration data that measures actual deaths, and that the data are inadequate in 128 countries where most louis vuitton sunglasses measles deaths occur. "As measles is considered for eradication, it will be crucial to improve surveillance to the point that deaths and cases will actually be measured, not estimated," they wrote. The WHO said that its Measles Initiative, in keeping with global strategy to battle both measles and rubella, is now called the Measles and Rubella Initiative. Margaret Chan, MD, the WHO's director-general, said in the statement that the 75% drop in deaths shows how effective well-run vaccination programs can be. "Now we need to take the next logical step and vaccinate children against Ray ban sunglasses rubella, too," she said. For measles, the strategy's goal is to cut deaths by 95% of 2000 levels by 2015, the WHO said. Goals also include eliminating measles and rubella in at least five WHO regions by 2020. Strategies also include high vaccination coverage, monitoring measles spread with lab-based surveillance, outbreak and case management, communication initiatives, and research and development. The 62 countries that aren't vaccinating against rubella are being encouraged to do so within their measles vaccine delivery system. CDC Director Tom Frieden, MD, said in the statement that rubella is the leading cause of congenital malformations in newborns. "This new plan outlines strategies we know work. It is time to partner with key countries to implement the plan in order to save our children from these terrible diseases," he said. The WHO said starting this year, developing countries can apply to the Global Alliance for Vaccines and Immunizations (GAVI) for financial support to obtain combined burberry handbags measles-rubella (MR) vaccine. Seth Berkley, MD, chief executive officer of GAVI, said in the statement, "With GAVI's $605 million [USD] investment for both the combined MR and measles second dose vaccines in developing countries, this is an historic moment for the reduction and hopefully eventual elimination of both diseases." Kathy Calvin, chief executive officer with the United Nations Foundation, said in the statement that $112 million more is needed to achieve measles and rubella goals for 2015. "We need significant commitments from governments and the private sector if we are going to stop measles and rubella, as well as the support of individuals worldwide, because a small donation from the public can go a long way and help save many lives," she said. Best known as a cosmetic therapy to banish facial frown lines, botulinum toxin type A, or Botox, was approved to prevent migraines in 2010, but only for patients who experience 15 or more migraine headaches a month. Today, about half of the $1.6 billion annual sales of Botox are from migraine and other non-cosmetic uses, a company spokesperson tells WebMD. In the new study, which appears this week in the Journal burberry ties of the American Medical Association, researchers analyzed findings from 27 trials that compared Botox to placebo and four studies that compared it to other migraine treatments. The analysis found that Botox injections were not effective for preventing migraines in patients who have less than 15 headaches a month. The treatment also did not appear to benefit patients with chronic tension headaches. But Botox-treated patients with chronic migraines and daily headaches had an average of two fewer headaches per month. Researcher Jeffrey L. Jackson, MD, of the Medical College of Wisconsin, says it is clear that much better migraine therapies are needed, especially for the most frequent sufferers. "All of the available migraine treatments benefit some patients and not others," he tells WebMD. "Until we really understand migraines it will be hard to design treatments that work well for all patients." He says that while the average Botox patient may louis vuitton handbags not experience big improvements, results for some patients might be dramatic. Botox Finding 'No Big Surprise' Headache specialist Satnam Nijjar, MD, of Johns Hopkins University School of Medicine, says the research analysis will surprise few clinicians working in the field. "This review emphasizes that most patients experience modest benefits, but we already knew that," he tells WebMD. He says most of his Botox patients have tried several drugs to prevent migraines and lessen their severity, and they either did not benefit or could not take the side effects. Anti-seizure drugs, such as topiramate (Topamax, Topiragen) oakley sunglasses and gabapentin (Fanatrex, Gabarone, Gralise, Horizant, Neurontin), are widely prescribed for migraine prevention, but these drugs can have side effects such as fatigue, dizziness, and nausea. But he says patients who don't like needles may find drugs preferable to Botox, which involves 25 to 30 small injections in the�head region every three months or so. Neurologist Robert Duarte, MD, tells WebMD that many of his patients who are helped by Botox are not bothered by the injections. Duarte directs the Pain Center at the Cushing Neuroscience Institute at the North Shore-LIJ Heath System in Manhasset, N.Y. "A significant number of patients that I treat experience fewer headaches and less intense headaches on this treatment," he says. "Many still require drug treatments, but they are feeling a lot better." Botox Maker Responds In an interview with WebMD, a spokesperson for Botox manufacturer Allergan Inc. says the study reinforces its role as a treatment to prevent chronic migraines. Crystal Muilenburg, Allergan's director of corporate Cheapest louis vuitton men t shirts sale white 2012 communications, says some patients in company-sponsored trials experienced a 50% reduction or more in headache days per month after two cycles of Botox, and more than 2 out of 3 patients showed some improvement.

2012年4月23日星期一

There are also unknown financial aspects of a successful asteroid mining operation

The migraine prevention guidelines will be presented at the American Academy of Neurology's annual meeting in New Orleans and published simultaneously in monster beats the journal Neurology. About 36 million people in the U.S. have migraine headaches, according to the Migraine Research Foundation. Migraines are painful, often disabling headaches that may be accompanied by nausea, vomiting, and sensitivity to light. For some, migraines are few and far between and respond well to available treatments. Others experience more frequent headaches that interfere with their life and don't respond well to treatments. The latter group may be candidates for the preventive treatments outlined in the guidelines. Preventive treatments usually are taken every day to prevent attacks from occurring as often and to lessen their severity and duration when they do occur. About 38% of people with migraine headaches could benefit from prevention, but less than a third of them use them, says guideline author Stephen D. Silberstein, MD, of Jefferson Headache Center at Thomas Jefferson University in Philadelphia, in a news release. Researchers analyzed studies on migraine prevention treatments to determine which are or are not effective. The launch of a commercial cargo ship making its first flight to the International Space Station is expected to slip a week or so to give engineers more time to complete pre-flight testing and analysis, Space Exploration Technologies, or SpaceX, announced late today. The company had been aiming to launch its Falcon 9 rocket and Dragon cargo capsule on April 30. A second launch opportunity was available May 3. Last week, NASA managers tentatively cleared the SpaceX rocket and capsule for launch pending completion of testing and a final review of open items and overnight Sunday, company founder and chief designer Elon Musk said in a Twitter posting: "Just completed the rocket rollout review at SpaceX HQ in California. Almost time to launch. Pucker factor increasing..." But this afternoon, after a review of the Dragon systems, Musk tweeted: "Am pushing launch back approximately a week to do more testing on Dragon docking code. New date pending coordination with NASA." Company spokeswoman Kirstin Brost Grantham said in a later e-mail: "After reviewing our recent progress, it was clear that we needed more time to finish hardware-in-the-loop testing and properly review and follow up on all data. While it is still possible that we could launch on May 3, it would be wise to add a few more days of margin in case things take longer than expected. As a result, our launch is likely Monster Beats Studio Lamborghini Limited Edition to be pushed back by one week, pending coordination with NASA." There’s gold in them there hills. You know, those ones floating around in space. Asteroids contain many tons of precious metals, making them irresistible to scientists, aerospace engineers, futurists, fiction writers … and tech billionaires. A group of wealthy, adventurous entrepreneurs will announce on Apr. 24 a new venture called Planetary Resources, Inc., which plans to send swarms of robots to space to scout asteroids for precious metals and set up mines to bring resources back to Earth, in the process adding trillions of dollars to the global GDP, helping ensure humanity’s prosperity and paving the way for the human settlement louis vuitton sunglasses of space. “The resources of Earth pale in comparison to the wealth of the solar system,” said Eric Anderson, who founded the commercial space tourism company Space Adventures, and is co-founder of a new company along with Peter Diamandis, who started the X Prize foundation, which offers prize-based incentives for advanced technology development. Nearly 9,000 asteroids larger than 150 feet in diameter orbit near the Earth. Some could contain as much platinum as is mined in an entire year on Earth, making them potentially worth several billion dollars each. The right kinds of investment could reap huge rewards for those willing to take the risk. Outside of NASA, Anderson and Diamandis are among the most likely candidates to realize such a dream. Space Adventures has sent seven private tourists to the International Space Station while the Ansari X Prize led to a spurt of non-governmental manned spaceships. “We have a long track record of making large-scale space ventures real,” said Diamandis. Despite the promise of astronomical profits, the long time-scales and uncertain return on asteroid mining has historically driven most investors away from such Ray ban sunglasses undertakings. But the new company is also backed by a number of other billionaire luminaries, including Google’s CEO Larry Page and executive chairman Eric Schmidt, former Microsoft chief architect Charles Simonyi, and Ross Perot Jr. The venture also counts on filmmaker James Cameron, former astronaut Tom Jones, former JPL engineer Chris Lewicki, and planetary scientist Sara Seager as advisers. Still, this new undertaking will be much larger and more ambitious than anything Anderson and Diamandis have attempted before. The hurdles are many and high. While the endeavor is technically feasible, the technology has not yet been developed. And beyond their initial steps, the details of Planetary Resources’ plans remain scarce. The first hurdle will likely be ensuring that Planetary Resources has covered all its legal bases. While some have argued that governments need to set up specific property rights before investors will make use of space, the majority of space lawyers agree that this isn’t necessary to assure the opportunity for a return on investment, said space policy analyst Henry Hertzfeld at George Washington University in Washington D.C. Mining occurs in international seabeds — even without specific property rights — overseen by a special commission dedicated to the task, he said. A similar arrangement would likely work in space. In terms of extraction, Planetary Resources hopes to go after the platinum-group metals — which include platinum, palladium, osmium, and iridium — highly valuable commodities used in medical devices, renewable energy products, catalytic converters, and potentially in automotive fuel cells. Platinum alone is worth around $23,000 a pound — nearly the same as gold. Mining the top few feet of a single modestly sized, half-mile-diameter asteroid could yield around 130 tons of platinum, worth roughly $6 billion. Within the next 18 to 24 months, Planetary Resources hopes to launch between two and five space-based telescopes at an estimated cost of a few million dollars each that will identify potentially valuable asteroids. Other than their size and orbit, little detailed information is available about the current catalog of near-Earth asteroids. Planetary Resources’ Arkyd-101 Space Telescopes will figure out whether any are worth the trouble of resource extraction. Within five to seven years, the company hopes to send out a small swarm of similar spacecraft for a more detailed prospecting mission, mapping out a valuable asteroid in detail and identifying rich resource veins. They estimate such a mission will cost between $25 and 30 million. The next step — using robots to remotely mine, possibly burberry ties refine ore, and return material to Earth safely — is probably the toughest phase, and Planetary Resources is still tight-lipped about its plans here. This is an unprecedented challenge — the only asteroid material ever returned to Earth comes from the Japanese Space Agency’s Hayabusa spacecraft, which successfully returned a few hundred dust particles from asteroid 25143 Itokawa in 2010. One possibility might be to find a useful asteroid and push it closer to Earth. A fairly low-power solar-electric ion engine could nudge a hunk of rock into orbit around the Earth, effectively creating a small second moon that could be easily accessed. A recent white paper (.pdf) written by a team of scientists and engineers for the Keck Institute for Space Studies looked at exactly this proposition in order to use an asteroid for scientific and manned exploration. The team concluded that the technology exists, though such a plan would need at least $2.6 billion in funding. If Planetary Resources went this route, it would rack up a large initial investment, which doesn’t include actually mining and returning material back to Earth, potentially adding many hundreds more millions of dollars. “It’s one thing to understand the mining and refining processes and another thing to actually build it,” said JPL engineer John Brophy, who co-authored the paper. “And everything in space tends to be harder than you think it will be.” Another option to simplify the process burberry handbags might be to bring the ore back to Earth for refining, though that presents its own set of challenges. Say for the sake of argument that you send a 5,500-pound robot (roughly the weight of a small car) to an asteroid and it can mine and carry back 100 times its own weight in asteroid material. On most asteroids, chopping up a one-ton chunk of regolith will generate less than an ounce of platinum. Even asteroids with the highest concentration of platinum yield only about two ounces of platinum per ton. This means that with the current commodity prices, each of your robot miners will generate about $875,000, even on an asteroid with the highest platinum amounts. Given a mission cost that is at least hundreds of millions of dollars, it wouldn’t be advantageous to refine ore on Earth. There are also unknown financial aspects of a successful asteroid mining operation. The sudden influx of hundreds of tons of platinum into Earth’s economy would certainly drive the commodity’s price down. Looking at historical analogues, the enormous gold and silver reserves the Spanish inherited from their New World conquests led to terrible inflation and possibly the decline of their empire. But Planetary Resources sees a platinum price louis vuitton handbags drop as one of its potential goals. “I would be overjoyed as a company if we brought back so much platinum that the price fell by a factor of 20 or 50,” said Anderson. Aluminum was incredibly expensive in the 1800s, before new technology allowed it to be easily separated from its ore, said Diamandis. Today, aluminum is used in hundreds of applications, something that Anderson and Diamandis would like to see happen to the platinum-group metals. While mining platinum and other rare metals is Planetary Resource’s way of bringing wealth to Earth, the world still has ample reserves of such material — South African platinum mines alone are expected to produce for another 300 years. “In my view, its questionable oakley sunglasses how the economics of asteroid-retrieval works if you’re going to bring it to the ground,” said Brophy. “It makes more sense if you’re going to use the materials in space.” Asteroids contain one substance that is of extremely high value for astronauts: water. Water can be used for drinking and it can be broken into its constituents. Oxygen is valuable for life support in space-based habitats, while liquid oxygen and hydrogen are both used to produce rocket fuel. Rather than having to lug all the fuel for a mission out of Earth’s deep gravity well — an expensive proposition — having a “gas station” in space could help enable missions to Mars and beyond. Such a refueling depot might allow people to permanently live and work in space, another goal of Planetary Resources. Of course, this creates a sort of chicken-and-egg problem. Do you generate tons of resources for your nonexistent space civilization first or do you get your space civilization started and then utilize the available resources? Wired Science’s resident space historian David S. Portree thinks asteroid mining might make more sense when we have a more established space-based habitats with a different economy and better technology. “Right now it would be like a big oil tanker dropping anchor off the coast of medieval England,” he said. “The medieval English might identify the oil as a useful Discount louis vuitton bracelets for women classic best outlet silvery commodity, but wouldn’t be able use enough to profit the tanker crew. Heck, they wouldn’t know how to get it off the tanker, except in wooden pails and rowboats.”

2012年4月22日星期日

She admits that she falls for it too

The study, of 218 women treated for early louis vuitton sunglasses breast cancer, found that almost one-third had "cancer-related fatigue" at the end of treatment. But far fewer -- six percent -- still had the problem a year later. That suggests for most women with the disease post-treatment fatigue will fade with some time, the researchers report in the Journal of Clinical Oncology. It's well known that cancer patients often suffer fatigue. And some studies have concluded it's common for that weariness to last for years after treatment ends. Among Ray ban sunglasses breast cancer survivors, researchers have found that more than one-third have fatigue two to three years after treatment. The reasons, though, have not been clear. And the new findings support the idea that some cases of chronic fatigue in earlier studies may have had causes other than the cancer itself. Past studies have often been "cross-sectional," meaning they studied people at one time-point. So it's possible to catch some bouts of fatigue that are related to various causes, explained Dr. David Goldstein, who led the new study. That could mean lingering fatigue from a viral illness, for example, or fatigue related to depression, according to Goldstein, of Prince of Wales Hospital in Randwick, Australia. "There are cancer survivors with true post-cancer fatigue," Goldstein said in an email. It's just that the number may be "less than previously thought." That may be true at least with early-stage breast cancer -- and possibly some other early cancers, Goldstein said -- but not necessarily more-advanced cancer. "The fatigue associated with advanced cancer is burberry handbags a much more complex issue -- tied up with the biology of an active tumor and its many physical effects, as well as the drugs used (for treatment)," Goldstein explained. The findings are based on 218 women who were treated for early-stage breast cancer with surgery and some type of "adjuvant" therapy, usually radiation, chemotherapy or both. The women answered questions about their physical and psychological health every few months for a year after treatment. Overall, Goldstein's team found, 11 percent persistently had fatigue at the six-month mark, while six percent still had symptoms a year after treatment ended. Goldstein said the study used a questionnaire that distinguished between physical and psychological symptoms, which some past studies have not done. And women who had persistent fatigue at six months were evaluated to rule out "alternative" causes -- like low thyroid hormone levels or depression. It's not clear why some women treated for early breast cancer remain fatigued for months or longer, according to Goldstein. Some recent research, he noted, has hinted that some patients could have a genetic predisposition to an "exaggerated bodily response" to chemotherapy, for example. Other work has suggested that chronic, body-wide inflammation could play a role. As for fatigue treatment, there's evidence that good sleep habits and regular exercise can help, if people can keep those habits up. Based on research into chronic fatigue, a combination of exercise plus cognitive behavioral therapy might help some patients, according to Goldstein. He said he and his colleagues are currently studying that approach. Cognitive behavioral therapy is a form of talk therapy focused on changing the thought patterns and behaviors that seem to be feeding physical or mental symptoms. One recent study also found that breast cancer survivors who got more omega-3 fats in their diets were less likely to have long-lasting fatigue than survivors who ate less. (See Reuters Health story of March 29, 2012) Omega-3 fats, which are thought to fight inflammation, burberry ties are largely found in oily fish like salmon, mackerel and tuna. Those findings, though, do not prove that omega-3 directly affects the long-term risk of fatigue. And the researchers said it was too soon for cancer survivors to be taking fish oil to battle fatigue. They noted, though, that eating fish a couple times a week -- something that's already recommended for general health -- could be a good idea. Imagine walking around with a tube that goes louis vuitton handbags through your nose and passes through your esophagus, right down into your stomach. A nasogastric tube, or feeding tube, provides nourishment. It’s usually reserved for patients with medical challenges. But now, feeding tubes are the new dietary rage. Last week, the New York Times ran a story about crash-dieting brides willing to undergo the 10-day K-E diet that costs $1,500 and requires a doctor’s supervision. It’s an eyebrow-raising trend, but oakley sunglasses we know where it stems from. The pressure on brides and women in general to look a certain way is not imaginary. When I was planning my wedding, every magazine had a get-fit-quick plan for brides. Looking a certain way was an ongoing dialogue. There was no escape from the endless pictures of Kate Discount louis vuitton bracelets for women classic best outlet silvery Middleton and even short-term bride Kim Kardashian. There’s nothing wrong with losing weight healthfully, but magazines, TV, runways and society seem to scream, “Lose weight. Look perfect.” Perfection is expected of women, not just by men, but by other women, because this is the culture of thinspiration and bodysnarking. We feel so insecure about our own image that we pick on others. I am no exception. I’ve been picked on for being too skinny and having acne. But I’ve also scoffed at the girls in too-short skirts and v-necks down to there. It’s the bullied becomes the bully complex. This is why Ashley Judd’s puffy face became beats by dr dre a thing to talk about recently. We all wondered if she was a victim of botched plastic surgery or a crazy beauty treatment. I shamefully admit I gave her face the questioning side-eye. And I know better. Still, it’s easy to get caught up in the crazy talk. In her essay for the Daily Beast, the actress blames the puffiness on steroids she was prescribed for an illness and takes us all to task over our obsession. “The Conversation about women happens everywhere, publicly and privately,” she wrote. “We are described and detailed, our faces and bodies analyzed and picked apart, our worth ascertained and ascribed based on the reduction of personhood to simple physical objectification. Our voices, our personhood, our potential, and our accomplishments are regularly minimized and muted.” She admits that she falls for it too. It’s one of those things in which none of us is completely innocent. And we must do better by our little girls and women. Judd says men and boys face the same pressure when it comes to fulfilling an image of masculinity. I think there are unfair expectations for guys. But I don’t think it’s the same as what women go through. On TV you can see a chubby, balding guy like “Modern Family’s” Jay Pritchett with the curvy and gorgeous Gloria. There is no reverse of that, not even in cartoon land with “Family Guy.” As long as a guy is funny, charming or talented, it almost doesn’t matter how he looks. Adele, one of the most talented singers in the world, was called fat by designer Karl Lagerfeld. But Ruben Studdard, once “American Idol’s” winner, was considered a “teddy bear.” Rapper Rick Ross, a Billboard regular known for his big belly, graced the cover of Vibe magazine’s sex issue last summer, shirtless. He has been called a sex symbol. But Jessica Simpson bares her naked, pregnant body on the cover of Elle and gets criticized for her weight. It’s called pregnant. There is no way for women to mold themselves into Monster Beats Studio NFL New Orleans Saints this image of perfection the media pushes. But there is a way for us to quit feeding into this unhealthy diet of body shaming and accept ourselves as well as one another. We cannot be reduced to our bodies, our faces and our clothes. We are much more than that. And it should be reflected in our conversations.

2012年4月20日星期五

Researchers led by James Tabor of the University of North Carolina

Regulators are proposing that food companies that want to use tiny engineered particles in their packaging may have to provide extra testing data to show the products beats by dr dre are safe. The Food and Drug Administration issued tentative guidelines Friday for food and cosmetic companies interested in using nanoparticles, which are measured in billionths of a meter. Nanoscale materials are generally less than 100 nanometers in diameter. A sheet of paper, in comparison, is 100,000 nanometers thick. A human hair is 80,000 nanometers thick. The submicroscopic particles are increasingly showing up in FDA-regulated products like sunscreens, skin lotions and glare-reducing eyeglass coatings. Some scientists believe the technology will one day be used in medicine, but the FDA's announcement did not address that use. The draft guidance suggests the FDA may require food companies to provide data establishing the safety of any packaging using nanotechnology. Under longstanding regulations, companies aren't required to seek regulatory approval before launching products containing established ingredients and materials, such as caffeine, spices and various preservatives. But FDA officials said Friday that foods and packaging Monster Beats Studio NFL New Orleans Saints containing nanoparticles may require more scrutiny. "At this point, in terms of the science, we think it's likely the exemption does not apply and we would encourage folks to come in and talk to us," said Dennis Keefe, director of FDA's office of food additive safety. Keefe said companies are studying whether nanoparticles can reduce the risk of bacterial contamination in certain foods. He said the agency is aware of just one food louis vuitton sunglasses package currently on the market that uses nanoparticles but did not identify it. He said more are expected in coming years. The FDA has previously stated its position that nanotechnology is not inherently unsafe; however, materials at the nano scale can pose different safety issues than do things that are far larger. "This is an emerging, evolving technology and we're trying to get ahead of the curb to ensure the ingredients and substances are safe," Keefe said. In a separate guidance, the FDA laid out suggestions for the use of nanotechnology in cosmetics, a practice which has been in use since the 1990s. Nanoparticles are used in skin moisturizer, mineral make up and other cosmetics. The FDA has less authority over cosmetics than food additives. Generally, the FDA does not review cosmetics before they launch, and companies are responsible for assuring the safety of their products. The FDA will take comments on both proposals for 90 days. There Ray ban sunglasses is no deadline for finalizing the documents. Long-unrecognized lettering confirms that first-century artifacts found within an ancient Jerusalem tomb are the earliest representations of Christianity ever found, researchers say. Two Hebrew scholars who examined photographs showing the inside of the tomb agree that markings on an ossuary — a box made to hold human remains — are stylized letters that spell out the name of Jonah, the researchers said Thursday (April 19). Jonah was the Old Testament prophet whose story of being swallowed by a great fish was embraced by the early followers of Jesus. The tomb, located 6.5 feet (2 meters) below burberry handbags an apartment building in the East Talpiot neighborhood of Jerusalem, was discovered in 1981 but resealed after Orthodox Jewish groups opposed its excavation. Two decades later, the group got license to enter the tomb, which has been dated to before A.D. 70. Researchers led by James Tabor of the University of North Carolina at Charlotte did not enter the tomb themselves but instead used a remote camera to explore it. Their analysis of the images was reported Feb. 28 in the journal The Bible and Interpretation. The Hebrew scholars' translation of the stylized burberry ties letters on the ossuary have yet to be published. On one of the ossuaries was an inscription depicting "divine Jehovah," and a second had a picture that appeared to be a fish with a stick figure in its mouth, said to represent Jonah. If they fully understand these drawings, the researchers said, then they have found the oldest Christian artifacts, the earliest Christian art and the first evidence of faith in Jesus' resurrection. Similar depictions of Jonah were used by later Christian groups and became an important expression of the faith in later centuries. When the tomb and its contents were first disclosed, many biblical scholars offered alternate interpretations of the iconography and disputed the tomb's connections to Christianity. They said the image is more likely a funerary monument and not a fish at all. [Religious Mysteries: 8 Alleged Relics of Jesus] After the initial announcement, the team continued to examine the images from their robot scout. Strange markings inside the fish head stood out to the researchers, louis vuitton handbags and they called upon James Charlesworth, a Hebrew script scholar from the Princeton Theological Seminary. The researchers said Charlesworth confirmed their interpretation of the marks: The lines that make up what they thought was a stick figure could also be viewed as four Hebrew letters. The script is similar to that from the Dead Sea Scrolls and seems to spell out "YONAH," the Hebrew name of Jonah. "This discovery by Professor oakley sunglasses Charlesworth is quite remarkable and had been overlooked in our initial analysis," Tabor said in a statement. "The engraver has apparently rather ingeniously combined what we took to be the stick figure of Jonah with the four Hebrew letters spelling out his name." Tabor also asked other Hebrew researchers for their opinion on the interpretation. Robert Deutsch of Haifa University confirmed Charlesworth's reading of YONAH, and Discount louis vuitton bracelets for women classic best outlet silvery Haggai Misgav of Hebrew University agreed there were definitely letters, but Misgav read them as "ZOLAH," Tabor said.

2012年4月19日星期四

The worst thing we can do to our people is to constantly change things

For some veteran astronauts, today’s transformation of the shuttle Discovery into a museum exhibit is a cause for celebration. For others, it’s a reminder of their louis vuitton sunglasses regrets. But for John Grunsfeld, the one-time “Hubble Hugger” who is now NASA’s science chief, the dominant feeling is a sense of relief. Discovery's handover to the Smithsonian's National Air and Space Museum has re-ignited questions about the end of the 30-year space shuttle program. Why did they have to be retired? The short answer is that in the wake of the 2003 Columbia tragedy, policymakers decided that once the job of building the International Space Station was finished, it would just be too risky and expensive to keep the shuttles flying. Instead, President George W. Bush decided to re-target the space program on destinations beyond Earth orbit. For Bush, the first focus was going to be the moon. President Barack Obama shifted that initial focus to near-Earth asteroids, but the endpoint is the same: eventually getting to Mars. And the shuttles could never do that. They weren't built to go beyond Earth orbit. Nevertheless, some of America's best-known astronauts Ray ban sunglasses think the shuttles should have been kept around a while longer — particularly because NASA will be dependent on the Russians for rides to the space station for the next three to five years. "The unfortunate decision eight and a half years ago to terminate the shuttle program, in my opinion, prematurely grounded Discovery and delayed our research," retired senator-astronaut John Glenn said during today's handover ceremony at the museum's Steven F. Udvar-Hazy Center in Virginia. Former senator-astronaut John Glenn speaks as the Smithsonian formally accepts space shuttle Discovery for permanent exhibition. Another retired astronaut who rode on Discovery, Tom burberry handbags Jones, voiced similar frustration during an interview conducted before today's ceremony. "I'm reliving the disappointment that the shuttles are retiring without a rapid successor," he told me. Jones wishes that the White House and Congress had revved up NASA's plan for new spaceships capable of going to the space station and beyond: the Constellation Program, which initially aimed to put U.S. astronauts back on the moon by 2020. Instead, Constellation was so cash-starved and technically challenged that the Obama White House scrubbed the program and reworked elements of it into the current plan to visit an asteroid by 2025. "We dropped the ball on this," Jones said. "If we just went from 0.5 percent of the federal budget to 0.6 percent, this would all be a non-issue." The benefit of retaining an American system for resupplying the space station is what motivated Glenn's call to keep the shuttles flying. Glenn made his pitch to the White burberry ties House in 2010 — but Obama didn't go for it, and the former Democratic senator told me today that he accepts the verdict. "No need crying over what happened in the past," Glenn said. "Let's get on with the future." The 'Hubble Hugger' and his pin Grunsfeld thinks the White House made the right call, at least on the question of grounding the shuttles. He's best-known for his role as a spacewalker on Hubble servicing missions in 1999, 2002 and 2009. During that last mission, Grunsfeld was the one who bade the Hubble Space Telescope goodbye forever. Now he's NASA's associate administrator for science. The way Grunsfeld sees it, keeping the shuttles flying might have led to another disaster like the 1986 Challenger explosion — or the loss of Columbia and its seven STS-107 crew members in 2003. "There's a possibility we could have flown them for a little bit longer, or extended them at some cost," Grunsfeld told me. "I'm actually extremely thankful that we are rolling Discovery into the Air and Space Museum, and not burying its parts. We flew out the space shuttle program gracefully. We didn't lose another one. It would have been tragic. The fact is that the space shuttle program was ended with louis vuitton handbags dignity — it was an amazing accomplishment, and I'm just thankful for that." Then he shared what he called a "small, personal story." "Just this morning, on my flight suit for the first time since the loss of Columbia, I took my STS-107 pin off. I felt like this was an apt celebration, that we flew out the program safely after Columbia, and that affected me very deeply," Grunsfeld said. "Now that we are where we are, I'm looking forward to getting the next space vehicle going." Retired astronaut Eileen Collins, who became NASA's first woman shuttle pilot during a 1995 mission on Discovery and went on to command shuttle missions in 1999 and 2005, has some firsthand knowledge about the risks associated with flying the shuttles. The 2005 mission on Discovery marked NASA's "return to flight" after the Columbia tragedy. She and most other people at NASA had thought they had solved the foam-loss problem that led to the Columbia's doom — but mission managers were shocked to see that the fuel tank shed a substantial piece of foam insulation during Discovery's ascent. No significant harm was done, but it took another year for NASA engineers to rework the problem to their satisfaction. This week, retired NASA shuttle manager Wayne Hale recounted the episode in a blog item headlined "How We Nearly Lost Discovery." Today, Collins noted that each shuttles was oakley sunglasses originally designed to fly for 100 missions or 10 years, whichever came first. Discovery, the most traveled of the shuttles, flew 39 missions ... over the course of 28 years. She recalled that she agreed with the shuttle retirement plan that was announced in 2004, but was disappointed when the Constellation Program was canceled in 2010. "At that time, I would say yes, we should keep the shuttles flying — with one major exception. Back in 2006, we at NASA made major decisions to start shutting down the pipeline for parts. In 2010, to reverse the decision and continue flying the shuttles was going to be very expensive and take a very long time. So it wasn't realistic to fly them again," she told me. "The worst thing we can do to our people is to constantly change things ... so in the end, the right thing to do was to fly out shuttle. I am personally very sad to see it go. But the big problem is, we don't have anything to follow on right now. We're going to get there. It's just that Discount louis vuitton bracelets for women classic best outlet silvery right now, we don't have it." It's not the end of the shuttle program that bothers Collins. Rather, it's the possibility that NASA won't be able to follow through on the beginning of the next program. Follow @CosmicLog "I don't want to see any more canceled programs," she told a school group after today's ceremony. "If we have problems, we need to fix those problems and press on. We can't just cancel and walk away from them. I go to schools, and I talk to kids, and I say, 'If you have problems, stick with it, fix it, don't give up.' We don't want to continue to give up on programs that are going to be taking us out into space, whether it's with robots or with people. We need to keep working on those programs." What do you think? Here's your chance to weigh monster beats studio in on the end of the shuttle program and the beginning of the next chapter in exploration. Just leave a comment below.

2012年4月18日星期三

To get Enterprise there from the airport in Queens

So, on Wednesday morning, three vintage warplanes louis vuitton sunglasses were trussed up and hoisted over the port side of the ship for a barge ride up the Hudson River to a museum near Schenectady, N.Y. They had to go to make way for the new star attraction: Enterprise, the prototype for the space shuttles that is due to arrive in New York City next week. Enterprise, which the federal government awarded last year to the Intrepid Sea, Air and Space Museum in Manhattan, is not scheduled to reach the ship for several weeks, but its move began commanding attention on Tuesday when the shuttle Discovery rode on top of a 747 jet from Florida to Dulles Ray ban sunglasses International Airport outside Washington. Discovery will displace Enterprise at the Smithsonian Institution’s National Air and Space Museum near Dulles on Thursday. After posing Enterprise nose to nose with Discovery, a crew employed by the National Aeronautics and Space Administration will lift the prototype onto the same, specially equipped 747 over the weekend. Then, the jet will ferry Enterprise to Kennedy International Airport on Monday morning, slowing along the way for a low-altitude tour of burberry handbags the Statue of Liberty and other New York landmarks. And so for the first time, a space shuttle will land in the city. That is, if the weather cooperates. On the sunbathed deck of Intrepid on Wednesday, much of the talk was about the forecast for untimely rain on Monday. “We’ve had a month of great weather,” said Susan Marenoff-Zausner, the museum president, as she apprehensively scanned the sky. If Monday is too inclement, NASA officials may decide to postpone Enterprise’s final flight, she said. As she spoke, workers guided a Douglas F3D-2 Skyknight, its black wings folded up to reveal the stars and stripes on their undersides, down to the pier below. The Skyknight, which did most of its fighting in the dark in the 1950s, took its place beside two foreign planes that were also being burberry ties jettisoned: a British Royal Navy fighter-bomber known as a Supermarine Scimitar F1 and a Soviet-designed Mikoyan-Gurevich MIG-15. Soon, the crane would move them onto an adjacent barge that resembled a floating Dumpster for the trip north to the Empire State Aerosciences Museum in Glenville, N.Y. Ms. Marenoff-Zausner said the decision to give up the planes was “bittersweet” because it would louis vuitton handbags help Intrepid accommodate Enterprise, which the museum’s directors hope will be a big draw. “With Enterprise coming, we had to make deck space,” said Eric Boehm, the museum’s curator of aviation and aircraft restoration. “And the only way to make deck space was to move three airplanes off. It’s hard to see them go, but it’s for the greater good. We’re going to get Enterprise.” The museum will need to attract a big crowd to help offset the costs of transporting the shuttle from Dulles. The bill for the move, which the museum had to pay in advance, came oakley sunglasses to $9.6 million, said Matt Woods, the museum’s senior vice president for facilities and engineering. Now, Mr. Woods’s staff must erect an all-weather tent, 56 feet tall, on the aft of the flight deck. They have begun reinforcing the steel deck to hold the Enterprise, which Mr. Woods says weighs about 75 tons. Already, a red outline of the shuttle’s distinctive shape is painted there, the nose aimed at the commuter ferry terminal in Weehawken on the New Jersey side of the river. To get Enterprise there from the airport in Queens will be a trial of its own. First, the cranes and stabilizers being used at Dulles to take Discovery off the 747 and put Enterprise on it must be dismantled and trucked to Kennedy. In the meantime, Enterprise will remain mated to the jet in a tent at the airport. In all, it will take about six Discount louis vuitton bracelets for women classic best outlet silvery weeks to get the shuttle off the plane and onto a barge. After a slow tug through Jamaica Bay, under the Verrazano-Narrows Bridge, through New York Harbor and up the Hudson to Pier 86, a floating crane with a 190-foot boom will hoist Enterprise onto the flight deck, Mr. Woods said. Once the shuttle is in place, Mr. Woods said, the tent — similar to the bubbles that cover some tennis courts — will be raised over it. By July, he said, the museum hopes to start selling tickets for entry into an exhibit designed around Enterprise that will cost about $3 million to build. Then, the serious fund-raising will begin. Later this year, Ms. Marenoff-Zausner said, Intrepid will start collecting donations toward a permanent structure, possibly a museum monster beats pro across the West Side Highway from the carrier with Enterprise as its centerpiece. “Ultimately,” she said, “we want to be able to create a permanent home for it.”

2012年4月17日星期二

The IN VIVO Blog: Take the PharmAsia China Survey, Get a Discount to PharmAsia Summit-Shanghai

Hello, I come to read your post again. Have a good day. Monster beats by dr dre headphones outlet-cheap over ear headphones, best in ear headphones

The study was funded by the Medical Research Council

A new technique to treat early prostate cancer may louis vuitton sunglasses have far fewer side-effects than existing therapies, say experts. A 41-patient study in the journal Lancet Oncology suggests targeted ultrasound treatment could reduce the risk of impotence and incontinence. Researchers say it could transform future treatment if the findings are repeated in larger studies. The Medical Research Council (MRC), which funded the study, welcomed the results, which it said were promising. Each year 37,000 men in the UK are diagnosed with prostate Ray ban sunglasses cancer. Many face a difficult dilemma: the disease kills about 10,000 men every year, but for some it may not get worse if left untreated. Standard treatment with surgery or radiotherapy involves treating the whole prostate gland, and can harm surrounding tissue, with a serious risk of side-effects, including urinary incontinence and impotence. Targeted treatment Doctors at University College Hospital in London have carried out the first trial using high-intensity focused ultrasound (HIFU) aimed at small patches of cancer cells on the prostate. Surgeon Hashim Ahmed burberry handbags explains how the treatment works This was a "proof of concept" study involving 41 patients. They used a probe, placed close to the prostate, which emits sound waves that heat the targeted cells to 80C, while causing minimal damage to surrounding nerves and muscles. Hashim Ahmed, a urological surgeon at the trust who led burberry ties the study, says the results, 12 months after treatment, are very encouraging. "We've shown in this study that focal therapy - by targeting the individual areas of cancer - can avoid the collateral damage. We've shown that nine in 10 men had no impotence and none of the men in the study had incontinence of urine." Mr Ahmed says the early evidence on cancer control is also very good. But he says this needs to be evaluated in much larger studies. "This could offer a transformation of the louis vuitton handbags way we treat prostate cancer. It could offer a cost-effective treatment for the NHS, and offer men with early prostate cancer an opportunity to treat their disease, but with very few side-effects." A patient on the trial, 72-year-old Robert Page, from Croydon, says his treatment, two years ago, was a great success. "The outcome was very good," he said. "I was very pleased with the treatment and very happy with the lack of side-effects, particularly when I contrast that with what might have been the case if I'd had one of the other, alternative, treatments." The study was funded by the Medical Research Council, the Pelican Cancer Foundation and St Peter's Trust. Further trials Professor Gillies McKenna, director of the Gray Institute for Radiation Oncology and Biology, a joint collaboration between the MRC and Cancer Research UK, welcomed oakley sunglasses the findings. "If these promising results can be confirmed in a randomised controlled trial, focal therapy could soon become a reasonable treatment choice for prostate cancer alongside other proven effective therapies." The chief executive of the Prostate Cancer Charity, Owen Sharp, also emphasised the importance of further research. "We welcome the development of any prostate-cancer treatment which limits the possibility of damaging side-effects, such as incontinence and impotence. These early results certainly indicate that focal HIFU has the potential to achieve this in the future. "However, we need to remember that this treatment was given to fewer than 50 men, without follow-up over a sustained period of time. "We look forward to the results of further trials, Discount louis vuitton bracelets for women classic best outlet silvery which we hope will provide a clearer idea of whether this treatment can control cancer in the long term whilst ridding men of the fear that treating their cancer might mean losing their quality of life."

2012年4月16日星期一

Despite the overall reductions in mortality for patients

The overall death rate from unintentional louis vuitton sunglasses injury among children and teens fell 29% from 2000 to 2009, a review of U.S. mortality data showed. However, despite improvement in the overall rate, rates of death by poisoning in young adults -- mostly from prescription drug overdose -- and suffocation in infants rose, the CDC reported in the April 16 issue of Morbidity and Mortality Weekly Report. And unintentional injury still accounted for 37% of all deaths in the 19-and-under age group in 2009 and was the fifth leading killer of patients younger than 1, the report said. Data for the report were collected from the CDC's National Vital Statistics System, which included death certificate data from the 50 states and the District Ray ban sunglasses of Columbia. The study categorized the mechanisms for death by unintentional injury as drowning, fall, fires and burns, motor vehicle traffic-related, other transportation-related, poisoning, suffocation, and other. Motor vehicle-related deaths were subcategorized by occupant, pedestrian, pedal cyclist, other, or unspecified. For all age groups, the overall accidental death rate declined except in those less than a year old, where the rate increased from 23.1 to 27.7 deaths per 100,000 from 2000 to 2009. The decline in the overall death rate was primarily the result of a drop in accidental motor vehicle-related deaths, which decreased overall by 41%, from 9.3 per 100,000 people in 2000 to 5.5 per 100,000 people in 2009. By subcategory, occupant burberry handbags and pedal cyclist deaths showed the largest decreases, by 47% and 52% respectively. In patients under age 1, suffocation was the primary driver of the increased overall death rate -- rising by 54% from 13.8 to 21.3 per 100,000 over the 9-year period. Although the overall death rate in patients ages 15 to 19 decreased over the study period by 33% (33.4 to 22.3 per 100,000), accidental poisoning deaths increased by 91% in patients ages 15 to 19 over the study period -- from 1.7 to 3.3 per 100,000. In a conference call Monday, lead author Julie Gilchrist, MD, of the CDC's Division of Unintentional Injury Prevention, said that empowered parents and safer environments could help curb accidental child deaths in the U.S. Gilchrist and co-authors noted that suffocation deaths in infants can be prevented by following safe sleep environment recommendations made by the American burberry ties Academy of Pediatrics. Those recommendations include always positioning an infant on his or her back, using a firm sleep surface, room-sharing without bed-sharing, and avoiding loose bedding. The increase in reported suffocation deaths also was partially caused by an improvement in differentiating between sudden infant death reports from accidental suffocations, Gilchrist said. Gilchrist also noted that poisoning rates in young adults, mostly attributed to the abuse of opioid painkillers, mirror those found in adult patients. Drugs were made available at home, at friends' homes, through drug sharing, or through alternate illegal sales. The researchers wrote that misuse of these prescription painkillers could be curbed through "appropriate prescribing, proper storage and disposal, louis vuitton handbags discouraging medication sharing, and state-based prescription drug monitoring programs." Despite the overall reductions in mortality for patients 19 and younger, the U.S. still has higher death rates compared with oakley sunglasses other developed countries for that same age group. Out of the 34 Organization for Economic Cooperation and Development countries, the U.S. ranked 30th in patients 14 and younger in 2008, "with a [death] rate four times higher than the top-performing nations," the authors noted. In 2004 and among patients 19 and Discount louis vuitton bracelets for women classic best outlet silvery younger, the U.S. had nearly twice the combined accidental death rates of the high-income countries in the World Health Organization's European and Western Pacific Regions. The report was limited by two factors: possible misclassification errors on death certificates and unintentional injury death reporting, louis vuitton sunglasses the latter of which may not properly underscore the total burden of accidental injury on society.

2012年4月15日星期日

If the patient struggles to pay for the drugs

Dole Food Co.'s fresh vegetables division louis vuitton sunglasses is recalling 756 cases of bagged salad, because they could be contaminated with salmonella. The bags of Seven Lettuces salads were distributed in Alabama, Florida, Illinois, Indiana, Maryland, Massachusetts, Michigan, Mississippi, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Virginia and Wisconsin. The company said the bags are being recalled, because a random sample tested by the State of New York came back positive for Salmonella. No other Dole salads are included in the recall. The recalled salads are stamped with a use-by date of April 11, 2012, UPC code 71430 01057 and product codes 0577N089112A and 0577N089112B, the company said. The product code and use-by date are located Ray ban sunglasses in the upper right-hand corner of the package, while the UPC code is on the back of the package, below the barcode. Dole said that it's coordinating with regulatory officials and that no illnesses have been reported. Consumers should throw out the recalled salads. Dole said it's also contacting retailers to make sure the bags in question are not available for sale. The most common symptoms of salmonella are diarrhea, abdominal cramps and fever within eight to 72 hours of eating the contaminated food. The illness can be severe or even life-threatening for infants, older people, pregnant women and people with weakened immune systems. Express Scripts aims to help patients stay on their meds with a product that predicts who will stop taking prescriptions before the person actually does it. The pharmacy benefits manager is launching burberry handbags ScreenRx, a program that uses a computer to sift through hundreds of factors that affect patients and forecast who is most likely to forget a refill or simply stop taking their drugs. The company then plans to contact those patients to help them stick with their doctor's orders. Express Scripts executives say their new program is focused on a big target. They estimate that about $317 billion in additional medical expenses were heaped on the U.S. health care system last year because people didn't comply with prescriptions. These additional expenses might include a heart attack for someone who stops burberry ties taking cholesterol medicines or an amputation for someone who doesn't adhere to diabetes treatment. The St. Louis company runs prescription drug plans for employers, government agencies and other clients. Chief Scientist Bob Nease said the data Express Scripts collects gives it a fairly good sense for factors that keep people from complying with a prescription. For instance, those less likely to comply include younger patients, parents with small children or men who have female doctors. People who live with a partner or are married are slightly more likely to comply than those who live alone. The analysis, called predictive modeling, doesn't delve into why patients stop taking their meds. It sorts through more than 400 variables that could affect a patient to see which people have enough red flags to warrant concern. For instance, a young, single male with a house full of kids who sees a female doctor might draw the program's attention. "You can think of it as a screening test," Nease said. "You want to identify people who are at risk ... before their symptoms arrive, and then you want louis vuitton handbags to intervene in a way that addresses their problem." Once a patient has been flagged, they receive a phone call. An Express Scripts representative will talk to the person to see if they need help. The PBM then might send the patient a pill box if they have a hard time remembering their prescriptions or a special beeper that goes off when it's time to take medicine. If the patient struggles to pay for the drugs, Express Scripts could provide information on assistance programs. Such a program could be useful, according to Dr. Michael Venturini, an Indianapolis cardiologist who estimates that as many as 30 percent of the patients he sees every week have trouble sticking with their medications. "Compliance is a large problem," he said, oakley sunglasses noting that the cost of the drugs is probably the largest reason behind it. Analysts say predictive modeling programs that aim to forecast patient behavior and improve care have been evolving in health care over the past few years, and the Express Scripts product is the latest evolution. "They have put a lot of money behind really trying to get the patient, the consumer to make good decisions," said Arthur Henderson, an analyst Discount louis vuitton bracelets for women classic best outlet silvery who covers Express Scripts Holding Co. for the investment banking group Jefferies & Co.

2012年4月13日星期五

Crosby for one said he was looking forward to visiting the city

We often liken NHL playoff games to burberry handbags chess matches. Imagine chess on nitrous oxide and you have an idea of the marvel that was Game 2 of this Eastern Conference quarterfinal between the Pittsburgh Penguins and the Philadelphia Flyers. This was an absolute blur of action from the moment Sidney Crosby scored 15 seconds into the game to the dying moments when Philadelphia rookie Sean Couturier completed an unlikely hat trick to put the game out of reach. It was a delectable stew of crushing body checks and raw skill that saw the Flyers complete an equally unlikely sweep of the first two games of this series with an 8-5 victory Friday night. For the second game in a row, the Penguins stormed out of the gate. Crosby's goal tied a franchise record for the fastest goal to start a playoff game as the Flyers got caught trying to make an immediate line change. And when Paul Martin scored with 17.2 seconds left in the first period to give the Pens a 3-1 lead, logic suggested the odds were long that the gucci sunglasses Flyers would come back for a second straight game. Uh. No. In spite of being outscored 6-1 in the first period of this series' first two games, the Flyers proved that they have been wildly undervalued as a Cup contender. "We're able to come back in a game like that again, I think it speaks volumes about the character in the room not only from the veteran players but the younger players as well," Flyers coach Peter Laviolette said. "Fighting back like that is not easy. Players were so resilient that it's unbelievable." What was unbelievable was this game. The Flyers scored two shorthanded goals. Two players, Couturier and Claude Giroux, had hat tricks. Giroux collected six oakley sunglasses points, setting a franchise playoff record. Couturier had four points, tying a franchise playoff record for most points by a rookie in a game. After climbing out of a 3-0 first-period hole in Game 1 to win 4-3 in overtime, the Flyers erased deficits of 2-0, 3-1, 4-3 and 5-4 in Game 2. Against arguably the most talented offensive team in the NHL, the Flyers went toe to toe, almost daring the Penguins to make mistakes. And when they did, Philadelphia made Pittsburgh pay. For long stretches of the game it seemed that every shift represented a glorious chance for one of these teams. Through two games, this series has featured 20 goals and left all of the hype looking somehow inadequate. Safe? Remember when the Tampa Bay Lightning coined the phrase "safe is death" en route to winning the Stanley Cup in 2004? Safe isn't even a word in this series' dictionary. The teams combined for four goals in the first, four Classic burberry bracelet cheap discount 2012 brown beige more in the second and five in the third; each time one went in you wondered if that would be the defining moment when winner was separated from loser. Even after the Flyers took their first regulation lead of the series on Jaromir Jagr's goal midway through the third period off yet another juicy rebound given up by Pittsburgh netminder Marc-Andre Fleury, the outcome remained in doubt. With little more than two minutes to go and the Penguins pressing, James Neal dove trying to poke a loose puck into the Flyers' goal. His effort narrowly missed and the Flyers went the length of the ice with Couturier completing the hat trick off a great feed from Giroux to make it 7-5. Giroux added an empty-net goal, but that's how close this wacky game came from taking one more pivotal turn. "We're obviously not satisfied again with the way we started the game. We'll have to find a way to start games better, but at the same time, once again we showed a lot of character and it's a big win for us tonight," said former Penguin Max Talbot, who at one point was going toe to toe with pal Kris Letang at the side of the Penguins' net 2012 chanel fashion sunglasses discount for sale CREWR248 with Letang giving Talbot a good slash across the legs. Like many in the Flyers' room, Talbot was disinclined to join in the raving about the dramatic elements of the game. "It's an 8-5 win, it looks really good," Talbot said. "Two guys get a hat trick. It's great for the media but for us it's not a win, it's Game 2. But Game 3 is going to be huge, so the sooner we can put it behind us the better." You would think that this style of game would serve the Penguins well. They have a solid nucleus of players that won a Cup in 2009. You might imagine that at some point they would be the ones to assert themselves and a Flyers team with five rookies in the lineup would stumble. Instead, it's the Penguins who have wilted as the Flyers have revealed themselves to be both resilient and relentless. "They're difficult losses there's no question about it," Pittsburgh coach Dan Bylsma said. Pittsburgh will skate at the team's practice facility late Saturday morning and then travel to Philadelphia for Game 3 on Sunday afternoon. Crosby for one said he was looking forward to visiting the city where he is reviled and emotions are often at a fever pitch. "I think it's a building that brings out the best in all of us," Crosby said. "It's always an intense and emotional game there and, given the situation we're in, we should be a desperate hockey team going in there." Defenseman Brooks Orpik, again a huge physical presence in the game, insisted the Penguins aren't looking for scapegoats only answers. "It's execution and realizing what you're doing wrong," Orpik said. "You've got to execute better and they're executing better and taking advantage of every mistake it seems like we make. "It's not effort, it's not guys pointing burberry ties a finger. We've got a tight group that works hard here. You can work through the mistakes we're making. It's not like you've got guys going in the different direction." At the outset of this series, most assumed it would be long and furiously contested. By Sunday night, we'll have a much better idea whether it will become that or something far shorter.

2012年4月12日星期四

The movie begins in a mysterious quasi-government base

The first thing you should know about "The Ray ban sunglasses Cabin in the Woods" is that you shouldn’t know too much before you see it. Consider the words "SPOILER ALERT" branded on any review you might read, including this one. If you’re determined to know more, I’ll tell you that director Drew Goddard and his co-writer, the uber-cool Joss Whedon (famous for "Buffy the Vampire Slayer" and soon "The Avengers"), perform a neat trick of mixology — pouring every horror-movie cliche you can think of (and a few you may have forgotten) into a blender, mixing until burberry handbags the blood is frothy, then adding heaping scoops of sharp humor. The result is a smart, and occasionally daring, homage to horror movies that both satirizes the genre and brings new life to it. Here’s where the spoilers start: The movie begins in a mysterious quasi-government base, where two white-collar drones, Hadley (Bradley Whitford) Oakley sunglasses and Sitterson (Richard Jenkins), are getting their coffee before their big day at work. Their office is a massive control room of some sort, and we soon learn that what they are controlling is the cabin of the movie’s title — a secluded, dark place that is the destination of five college students on a spring-break getaway. You know, the sort of place that only exists in slasher movies. The students fit the archetypes, too. There’s the jock guy, Curt (a pre-"Thor" Chris Hemsworth), and his randy girlfriend, burberry watches Jules (Anna Hutchison). There’s Curt’s hunky nice-guy pal, Holden (Jesse Williams), and Jules’ slightly shy roommate, Dana (Kristen Connolly), whom Curt and Jules aim to pair up. And, in the role of fifth wheel, is Marty (Fran Kranz, from Whedon’s "Dollhouse"), the stoner conspiracy theorist. True to form, the five students get to the cabin and immediately start exhibiting the behavior common in horror movies: Getting horny, finding mysterious artifacts that have secret curses, then inexplicably splitting up at the moment they should be banding burberry ties together. What they don’t know, and we do, is that this behavior is being controlled by Hadley and Sitterson and a crew of hundreds. Goddard, a writer for Whedon’s "Buffy" and "Angel," and his old boss pay tribute to the horror genre’s conventions, while also playfully tinkering with them. This is especially true in a gleefully chaotic sequence near the movie’s end, which riffs on so cheap burberry shoes 2012 many famous horror franchises that fanboys will be wearing out the "pause" buttons on their remotes the second this movie hits Blu-ray. But in all this recycling and ironic referencing, there’s something more sly at work. Cheap Bvlgari sunglasses, wholesale Bvlgari designer sunglasses 2012.Goddard (who wrote the screenplay for "Cloverfield") and Whedon explore what makes horror work, what draws us to these scenarios time and time again — and also why what’s scary in, say, Japan isn’t scary here. It’s pop-culture anthropology louis vuitton scarves brilliantly disguised as a blood-drenched thriller, and raises "The Cabin in the Woods" to a higher level of gory fun.